Michelin Defender 2 LTX M&S. Very quiet on the highway, enhanced gas mileage, excellent on wet roads, decent in winter driving conditions (for me) and great tire life.
Ran them year around in CO when commuting over the continental divide (Eisenhower Tunnel) several times a week for work, running around the back country, etc. Same up here in British Columbia. Have them on an F150, F350 with cab-over camper and on the wife's Xterra. Over 25 years experience with them without flats and no unplanned trips into the ditch.