It depends on the hunt for me. I almost always have a fixed blade on my belt or in my pack. Usually a pretty high quality one with a 4-4.5" blade like a Bark River in 3V or Dozier in D2.
For the second knife it depends a bit if I will have the fixed blade on my belt or in my pack. Some of my newer pants have a built in belt that I don't really like carrying the fixed blade on. My Kuiu rain pants have the belt covered for most of it's length. Due to this I'm carrying the Dozier with it's formed kydex sheath more in my pack and a folder in my pocket. Sometimes I carry a Benchmade Altitude in my bino harness and don't take a folder. If I hope to be caping an animal and not doing a Euro mount I'm more likely to have the Altitude.
I like the Bugout others mentioned but don't consider it real sturdy like they said. I do carry it quite a bit since I have the fixed blade on day hunts for deer.
For longer trips or hunting bigger animals I like to go with something a bit tougher. I have 3 I pick from:
Buck Alpha Crosslock in S30V. This knife has the saw/guthook blade and a 3" S30V blade and weighs 3.9oz. Biggest drawback for me is it's a little thicker knife and doesn't carry in a pants pocket as easy as the others. The guthook is pretty wide and can save the edge on other knives doing hide cuts though, especially on animals with a thicker or muddy hide. This one goes more often if the fixed blade is on my belt and it will be in my pack.
Gerber Bolt Action Exchange blade. This knife weighs 2.5oz with the utility blade I use for camp work. I like that it can quickly swap blades to a saw or different shaped blade. I sometimes take this as my only knife and leave the fixed blade. If I ever lost the knife from my pocket I could still process game using the spare blades I carry in my pack and a little tape. Biggest downside is that it's just standard Gerber stainless steel from the 80's or 90's. If I ever find someone to build me some S30V blades to fit it I'll likely carry it all the time. I usually carry the knife in my pocket and a couple spare blades in my pack. The knife with both spare blades in the sheath I use is 5oz total.
ZT 452CF. This is a 4" S35 blade, a bigger knife but light for it's size at 4.4oz. I took it to Alaska on the moose hunt and it worked well. The blade shape is identical to the Benchmade Saddle Mountain Hunter knife, a pretty good slicer for meat but not the best skinner. I like a bigger knife especially on something the size of a moose, so it was a great fit there. It's almost as capable as my fixed blade for camp work but still easy to pack.
A knife is one place I am willing to pack a little extra weight. I like knives and consider them important enough to carry 2 of them almost all the time. I'm also pretty good at losing them, that might be why I like having 2 so much.