To me, 20 grains isn't worth the effort in itself. But if you were to combine that with something like adding 5# of draw weight or a faster bow then it's measurable.
I made an arrow speed calculator the other day for people to play around with. It's based on a good sized dataset with actual chronograph data at varying lengths and weights. I find it a little more accurate than others out there, but none are perfect. This one lets you detune the IBO so it's closer to reality. Most bows I find are about 5% lower than advertised.