I ran a 6.5 grendel for a bit. Loved it. Knocked coyotes down without issues. Ended up selling it due to all the ammo issues. Its been almost 2 years and Im just now seeing powders, bullets, primers slowly starting to show back up. great round.
I went back to 223 and really enjoyed it. I had way more 223 reloading supplies laying around then I did 6.5 grendel, so Ive been living off that for a while. Also gets coyotes, but not with the same hammer effect of the heavier grendel rounds I was using.
I have some friends who are really loving the 6ARC, but that 224 Valkyrie is hard to beat. Also it seemed like over the last 2 years of ammo shortage, I always came across 224 valkyrie ammo sitting on shelves.