I would FAR rather carry a .30-06 when hunting RM Goats or Elk or Moose, in Grizzly country than ANY 6.5 bore ever made. Actually, I consider this with a 200 gr. Npt. to be "ideal" for this use and better for many shooters than the .338WM, 9.3x62 and .375H&H, as it is easier to shoot fast and well.
Goats, ARE "tough" and live where you may need to anchor one with ONE shot or they struggle over a cliff and end up smashed to bits. I have never bothered to shoot one, just not interested, but, have seen some shot here in BC, during my years working for our resource agencies and in AB, as well.
I used to own, 50 years ago, one of only two Mannlicher-Schoenaur 1961MCA carbines I have ever seen in 6.5x55, (NOT a misprint) and it was a drill. I was young, fit, working in the Kootenay mountains for the BCFS and hunted hard. Yet, when hunting Elk,or, where Grizzlies were especially numerous, I carried my first P-64 Alaskan, .338WM and felt better with it, especially alone.
I agree with the gentleman above, I never depend on ANYONE else for MY safety in the bush.
JMHO, it's better to have lots and lots of rifles, anyway!