Driving up in a uhaul isn't too expensive for a pair or trio, if going alone then flying in won't be much more expensive. Just remember, when calculating gas, add about $3-$4 a gallon over the current price in Fairbanks, and be ready to pay it (you will have to prepay before you pump, cards are accepted but cash is safer and you dont have to worry about the card machine being down). I caution people wanting to drive up to the Arctic Circle all the time, once you leave Fairbanks there is nothing between stops and you have to pay the price. Pay attention to real MPG you get at each stop (not the gauges/readouts) and do math. You will absolutely hit points of no return where if you cross a certain line the only way back is 80 miles forward. Just know where those lines are. Getting a copy of the Milepost guide is the best money you can spend on this trip (if you drive). Do not rely on any digital maps to tell you where gas is, use the current years milepost guide.
To echo everyone else. Spots mean nothing, the herd moves. But, pay attention to the ADF&G website, phone lines and Facebook pages. You will have rough ideas of where to pinpoint your trip start once you land in Fairbanks. Be flexible, don't get emotionally attached to a location if the reports say the herd has passed that area or hasn't made it there yet.
Also, look up your cell phone company coverage maps. Not all companies have great reception in Fairbanks. Do not rely on being online for anything once you hit Fairbanks (have ADF&G numbers saved, maps downloaded... etc).
Finally, while in Fairbanks. Lock your damn doors. If you park at the Fred Meyers or Walmart to grab something, just expect someone will try to open your door. In a rental your all the more a target. Lock your doors, don't stay inside the store forever, don't let your gear sprout legs. Most out of staters are shocked at the levels of homelessness and crime in Fairbanks (not to mention Anchorage). Just something to keep in mind as your not going to have a bunch of options if someone walks off with your backpack.
Good luck, Alaska is a phenomenal place. I may see you on the road!