I had my first 175 ELD-X kill over the weekend with about a 100lb whitetail buck. Impact velocity was a modest 2500 FPS - not screaming fast, not super slow - and I slipped it just behind both front shoulders so I didn't loose too much meat. However, had I nicked a shoulder, I'm sure I would have lost a LOT of meat - wow... That thing was an absolute grenade inside the chest cavity.
On post mortem, it had shredded both lungs, the liver, AND some of the guts on the way through, and left little chunks of lead and jacket everywhere. If I was visualizing the swath of destruction, I'd say it's probably about the size of a basketball on the inside. I presume this is because fragments were spreading out in all directions. There was an exit, so at least some percentage of it held together and went all the way through, but it sucked a piece of lung out of the hole, so the blood trail was kind of sparse. Luckily he only went about 30 yards, so it wasn't a big deal (and maybe he would have bled better had he gone farther).
Anyway, it obviously worked, and if the goal is to create as insane a wound tract as possible, these appear to be really good at that. That said, if I had dropped this in a shoulder, I have 0 doubt I would have lost the entire shoulder (possibly both if it hit both of them on the way through), just for concerns of lead fragments if nothing else.
Since accuracy/shot placement trumps almost everything else, and in this gun, these are far and away the most accurate bullet I've tried, I'll keep running them in this one. But I remain not convinced that this is the best way to harvest meat; I think an Accubond with a smaller wound tract (that is still more than adequate if you pump it through the chest cavity) would leave me with more and better eating.