My gun (T/C Encore Pistol 15" barrel) has a definite preference for the heavier (115 gr. bullets). Factory velocities are easily duplicated with RL-19 (Federal w/117 Sierra). The accuracy leaders so far are A-4350 and H-4832SC. I am doing some testing with RL-22, RL-25, and IMR-7828, and will post the results at a later date. My standard primer is the Federal LR (F-210), and I sometimes use the Federal Magnum Primer (F-215) with the larger charges of RL-25 and IMR-7828. My method is to mike the case head of an unfired factory case and a fired factory case, and keep my loads within those expansion limits. I tried the Nosler E-Tip 100 gr. bullet, but blew a primer on a less than max load. I requested some e-tip data from Nosler, but got nothing, so I used Barnes data as a starting point. The Encore chamber has very little freebore, and cartridges loaded to the SAAMI max. OAL of 3.250 contact the rifling, so my max. OAL in this gun is 3.238, which could account for the higher pressure. More on that project later. I use both R-P and Federal cases, and have just received some Nosler cases which I am anxious to try.