I have a stock (besides running boards and a tool box) 2011 Silverado 1500 LT w/ ~239k miles on it.
I have done all of my own oil changes, tire rotations, and brake replacements.
At 100 & 200k miles I took it in to the Chevy house to have them change the diff fluids, plugs, and other routine things.
I've only had 3 problems with it: a computer chip issue and a cracked transmission fluid tube, both covered under warranty; the other was replacing a hub bearing that I tore up during an elk hunt going down a road that a full size truck had no business being on with zero turn arounds.