I do. I work from home 100% of the time and have a dedicated office. I use TurboTax to file and just answer the questions honestly. I haven’t had any issue.
My wife and I both work from home a substantial amount of time. My accountant advised us not to take the deduction, he stated it huge flag and seems to garner more scrutiny then it should. He advise other ways to take liberal deductions that has less chance to trigger audits and yet save more in taxes.
Just to add clarity here, are the folks doing this also business owners? There seems to be a difference WFH employees and WFH owners.