I'll be in moose camp in a few days. We'll have a 30-06 and 280ai both in the 160gr range. It'll do the job if it's in a leathal zone and it won't if it's in the guts. But then neither would a 338mag. Anything short of a cannon that takes the back half of the moose off will require a follow up if it's a crap shot.completely understood. But if you think the guy hunting moose as a local after work wouldn't hunt differently if he had to travel halfway around the world to do it, you're wrong. Also, misses happen. Misses of the "ideal" spot you were aiming for. wouldn't it be nice to know if you do screw up that the gun could compensate and give you an extra, say, 10% efficacy? Especially if you can handle the gun?