My thoughts are that there are a lot of good options.
Stone glacier really impressed me. The frame was comfortable with a load and the packs are super light. The new sky bags with the center zip access are definitely handy, plus they shrink down pretty well in "bivy" mode. For me, the new three piece belt was more comfortable than the original belt. Kurt, the owner/designer was there and was super helpful and willing to answer any questions I had and set the packs up in any configuration I wanted.
Mystery ranch has a new "lift kit" which, in my opinion, fixes the shortcomings of their frame. I ran a Metcalf last year and while it was definitely more comfortable than the crew cab I had before, due to the built in extension, the extra comfort was lost when letting the pack away from the frame to carry meat. According to the guys at mystery ranch you can pull the built in extension out of the Metcalf and then run the "lift kit" on the frame with no weight penalty. This way you can let the pack away from the frame to carry meat and maintain load lift.
For me, the kifaru frame was the most comfortable. Especially the bikini frame with the "flat back" stays. Their frames are sturdy and infinitely adjustable. The number of pack, pocket and lid options is mind boggling. The nomad and emr 2 definitely have my interest. The emr 2 is huge. If you can't put it in that pack, you don't need it! That being said it compresses down extremely well into a user friendly day pack mode. The nomad is a very versatile pack and might be better for my needs now that I'm once again living in California. : ( The customer service was awesome. They switched frames, belts and took their time to make sure everything was fitting properly.
The kuiu frame is very space age looking and is very light, but was the least comfortable for me. The packs had some nice pocket configurations and were also very light but seemed the least durable of the bunch. That being said I know a lot of people like them. They also had a couple new tents that looked pretty interesting.