Inside 20 yards. Clear path. Calm breath. I'd shoot. 20 yards is a good cutoff distance for that shot for me. Anything further than that and I would pass.
Bigger target but some damn tough bones up front. The way the ribs start on the front of an animal aren't super arrow friendly depending on the frontal angle. A good broadhead will blow right through these on a deer, an elk it should but strange things happen. I feel more confident blowing through these bones on a deer. Not confident =Me not shooting simple as that.
I'm ok with it. I know where to shoot and as long as the stars are aligned i will take the shot (don't think i would do it beyond 25-30yds though). I also shoot a lot of KE and MO so i feel i have a little leeway if i hit bone.
My very first year of bowhunting I passed on a 5x5, frontal at just under 20. Should have shot--but didn't feel comfortable with it at the time. Now would be fine with it, at 20 or less. Everyone has their own comfort zone.