What you may "gain" in better BC with the 80 ELDMs can be lost with generally narrower wounds out of both the 80 and 88 M's. This is not to say that the 80 and 88 M's don't kill and perform well, it's just that in what I've seen, and what others have also observed, the 77 TMK's and 80 ELDX's are THE consistent .224 killing bullets.
If your 22 Creed shoots the 77 TMK's accurately I'd keep rolling with them. If you want the BC "edge" while still maintaining very consistent killing wounds then go to the 80 X's. As an example, even in 10+ MPH cross/shifting winds, there has been no observed increase in "hit rate" out to 1,200 yards when comparing the 80 X's to the more ballistically dominant 88 M's. At the ranges and wind speeds where it "may matter" you aren't shooting the difference in a hunting gun from a hunting shot position.
For practice, shooting the cheaper 80 M's and then moving to 80 X's is what I'd recommend. I have 3 Tikka 22 Creedmoors currently and switch between 80 M's, 88 M's, 77 TMK's, and 80 ELDX's throughout the year shooting. When it comes time to hunt big game, either 77 TMK's or 80 ELDXs will be in the mags.