I have reloaded for .300 WM in the past and actually just got a new .300 winmag in that I have loaded some rounds to test out today using H1000 with both 210 Berger VLD and Nosler 210 accubond LR. I live up in Fairbanks and it will likely be negative temps when I first take velocity readings, I will take them again using the same load in summer to have an accurate velocity as well as note the change/sensitivity as I have been seeing more info come out recently about one powders sensitivity relative to another. May even load another powder to see the differences, have some extra time to kill over christmas.
The temperature of the powder absolutely does effect muzzle velocity (as others have said) in the way one would logically think. The warmer the powder the higher the velocity. That being said unless thier is a drastic difference in temp the slight change in MV is unlikely to to change your POI enough to account for it at standard hunting distances.