I think you'd be fine either way, but if I had to choose one of the two I'd go with the .22 ARC. Keep in mind this is just conjecture and opinion, but it looks like you get a disproportional increase in velocity with the .22 ARC over 6 ARC. Something like 3300fps vs almost no loadings for 6 ARC getting above 2950, with an awful lot of them being around 2600 for the heavier grain weights.
Also, admittedly it's a bit voodoo, but I suspect there's an inflection point starting around 3000fps where terminal ballistics start working differently than with slower and heavier bullets. Things seem to get more explosive, rather than relying on blood loss from crushing and penetrating deep. A good example might be .243 - people seem to get better terminal effects on deer with bullets in the 58-70gr range than the 90-100gr range, especially with modern bullets. More bang-flops or just staggering a few yards, than the 100yd runs. But that seems to only start around 3000fps - Federal's 95gr Fusion load for the .243 is still right at 2950ish, but Hornady's 75gn is over 3500fps. Hornady's 58gr is just shy of 4000fps.
It also seems that some bullet construction mimics this explosive effect - 77gr Sierra TMKs in .223/5.56, for example, even though it's usually only going around 2600-2700 at the muzzle (be very careful with advertised muzzle velocities, especially with AR ammo - it's almost always tested out of a 24" barrel, so plan on subtracting about 25-50fps per inch of barrel loss). There's a long thread on here showing the effects of this bullet on deer and even elk. But I'm not aware of people getting the same devastating performance out of heavier grain soft-point .223 ammo going at the same velocities.
One of the things about the .22 ARC I'm particularly interested is their new ELD-VT bullet - it's got a pretty big hollow cavity at the front that, at least in theory so far, should lead to some pretty explosive terminal impacts.
So between the two, I think there's a better chance to get both a flatter shooting and harder hitting round with the .22 ARC over the 6 ARC - it seems you can get .22 ARC screamin' fast more easily than you can 6 ARC, especially when also trying to use high BC bullets. The velocity numbers between the two ARCs are pretty far apart from each other, in ways that probably make more of a difference than, say, the difference in terminal effects between .22 Creedmoor and 6mm Creed.