This is what I do specifically for pellet smoking. Strategy is similar for an a traditional offset smoker but you need to make some modifications based on how the pellet smokers cook...
.Brine it in a sealed tub overnight, at least 12 hours
.Remove from brine, rinse gently, and pat dry
.Let it sit out and get to room temperature
.Apply your dry rub liberally, coat all sides
.Get your smoker going and up to consistent 185 degrees
.Place roast in foil tray with 1/4" inch of 50/50 apple cider vinegar/water in the bottom of the pan, generous slices of butter in each corner of the pan, get your water/cider vinegar mix in a spray bottle and spritz every hour or so. Add more to the pan as needed as it cooks, don't overuse though.
.Keep a temp probe in the center and make sure it isn't getting up to temp too fast, at these temps it will take many hours to get to about 120 internal.
.At 120 degrees take the roast out and wrap tight in good quality butcher paper, spritz the butcher paper with your mix
.Put it back in the smoker with the temp turned up to 205 degrees, place wrapped roast straight on the "cooler" side of your grill (these smokers always tend to have a hotter and cooler side).
.Move your aluminum pan down to the deflector shield under the grill to block the direct heat from the bottom, essentially making it a drip tray directly under the roast. Make sure there is about 1/2" of your water/cider vinegar mix in the pan
.Once your internal temp is 140 remove from the smoker, leave it wrapped tight and place in the oven with the oven turned off
.Let it rest in the oven for 2 hours, this will bring it up to about 150 internal and then begin to cool down
.Remove from the oven, remove the wrap, and let sit for another 15-30 minutes
.Slice with a very sharp knife to serve
.I like to make a nice glaze to drizzle on the slices, both sweet and spicy glazes are good choices.
I like to make little slider sandwiches with a spicy glaze and pepperjack cheese, or a sweet glaze with a sharp cheddar. Enjoy!