Btw, since you're brand new you probably haven't seen or been told but the quoted portion below will likely get you poor or no responses. I don't mind sharing some info since the hunting, and wildlife outlook are so different in the Midwest vs the West but many others will assume you're here to get good info and never return without contributing to the site.
Best will be relative, deer numbers are good across the state but the highest scores usually come from central and northern MO. I would expect pressure from other hunters to be moderate to high. Unless money and time aren't a consideration you may want to work out the logistics of hunting each each area(s) before diving into specific conservation areas since many don't allow dispersed camping and travel time between home/hotel to those areas may be significant. Camping in the parking lots can be....interesting.
If you're on Rokslide long enough, and have interest, I can help you out with more specific info about a few CA's in the northern portion.