Deer densities are low in both districts.
Hunting pressure in the Missions is surprisingly high, especially given the terrain and rudimentary trail system. Used to be good hunting. Lately, not so much. I dont hunt it anymore.
150 is an interesting option. Not as many deer hunters (tons of elk hunters). Access is difficult (long trail distances just to get to the district border) and best off horseback. Deer densities are very low, but some nice deer come out every season. Be prepared to be extremely patient. If you are prepared to REALLY go deep, you can find some solitude.
Absolutely critical in these districts to be bear aware and prepared. Plenty of grizzly bears.
Good luck!