I have 4 kids at home so football and fall sports are rampant in my household. Family time is always treasured and sorely missed when i took my last 2 trips out west.
My advice would be to wait until your kids are old enough to hunt with you and go that route. Obviously you miss family time, why try and fight it? Thats not a knock on you - you love your family. Get them involved ASAP - they'll likely be more reliable than any hunting partners you can dredge up on the internet.
I typed the long response below before I seen this post - I'm gonna leave it as advice for others.
My wife is really not keen on me going by myself and if i want to keep heading out on far away excursions i need to have her mind at ease. Plus i am leaving here home alone with 4 children so i don't want to add anymore undo stress. I used the garmin inreach the past couple years but she still has voiced her unhappiness on me going alone. Going with a complete stranger might not be any better, but i think mass murders don't really visit hunting sites to prey on poor lonely hunters.
I tried to do a 3 day Whitetail hunt in southern Illinois (just 4 hours from home) and it totally sucked. i gave up after 2 days. I hate being by myself and the idea of being in the unknown mountains in a tent in the dark all alone really doesn't appeal to me. (the boogie man is out there....i know it) Plus you all have animals bigger than coyotes.
It takes acclimating just like anything else. The only animals I'd concern myself with are grizzlies, and AFAIK Colorado is grizzly free for now. My state(Washington) just has black bears which I'm not in the least amount scared of, as well as wolves and cougars. I don't worry about the cougars, either.
I'll agree that sometimes, during some hunts it can be boring... bear hunting especially. You're sitting on a hillside waiting for yogi to pop out somewhere. During those times I'll have books downloaded on my phone to read off-and-on while glassing. Coming back to camp after hunting, its getting your dinner cooked up(if you didn't eat while you were out) and then turning in. If you find it hard to sleep you can do more reading, listen to ebooks/podcasts, or have some movies downloaded to your phone.
Upgrade your Inreach plan to unlimited and you can shoot the breeze with your wife while you're out... its well worth the extra money. I downgrade my plan to the basic plan during the offseason to offset the costs, but during season I'm able to communicate whenever/wherever.
The first night is the hardest - I usually take Benadryl to help carry me off to sleep... once I'm over that hump I'm golden.
Another thing is having a comfortable camp setup. While backpacking is a slightly different story, if I'm hunting out of my truck I have a fat mattress that's seriously 95% of the way to my mattress at home(Thermarest Mondoking), I bring the pillow off my bed, and I have one of those massive mountain trapper sleeping bags. If its during late fall/winter I have stove jacks in a few of my tents - another "activity" once back at camp to stave off any boredom.
I have no advice on the wife - maybe talking with her and seeing what you could do to make her feel more comfortable with the idea? My wife is perfectly fine with me being out by myself.