Does the 43x have the gen 5 Glock Marksmanship Barrel (GMB) barrel in it? If so, you're clear for lead. The pre-gen 5 barrels with polygonal rifling are no-go for lead. Although there are reports of people using hard cast and some who will say they will shoot a couple mags and then clean thoroughly after, its not advised by manufacturer. The gen 5 GMB's are cut differently and safe for lead. I would be cleaning afterward regardless. In general, as a reloader, I avoid lead since it requires extra prep and has to be loaded a little slower. If you're reloading, try plated. Its advertised to load to lead specs but it can be pushed faster in my experience.
In relation to +P or +P+, there should be a little pentagon after the serial on the barrel. If it has that with a dot in the center of the pentagon, it is +P rated. I don't think any +P+ ammo is recommended by any manufacturer. In a piece as small as a 43x, I would be a little shy to use +P+, its a handful. Most guys I know who run ammo that hot are using it to reliably cycle Uzis and similar that have stiffer recoil systems.