Galliprant for dogs with osteoarthritis

[Gutshot007]

My old lab has some osteoarthritis . Has been on glucosamine/chrondrotin seemed to help some. Tried carprofen min results . Talked to my vet i guess galliprant is a new one out . Were gonna try it a couple weeks . Anyone have any first hand experience ?

 

[HarvestMoonOutdoorsman]

I think Carprofen is the same thing as Rimadyl and I'm surprised you had minimal results. It improved my dogs quality of life exponentially for her last couple of years. That was going to be my recommendation.

 

[Gutshot007]

She had a bout of anaplasmosis last year and was treated with doxy . That also i think has added to things

 

[homebru.trout]

Carprofen worked initially with my lab but wasn't a long term solution. We switched to Galliprant and are now on to Galliprant + Gabapentin (nerve + NSAID).

As with my last lab, when "the two G's" stop working and quality of life declines substantially again, we'll likely make the hard call.

 

[steelheadmike]

We have a 12yo BLF with arthritis that would have trouble putting weight on one of her back legs when she would get up from her bed (especially a after going for a walk). She would hobble around for a few minutes before she limbered up.

We tried glucosamine and some Gabapentin but it didn’t seem to make a noticeable difference. Our vet suggested Gabapentin but was hesitant as our dog had some elevated liver markers. We started her on it and monitored her liver.

It has worked wonders. It takes a few days for it to kick in but she doesn’t have any trouble getting up any more and seems to be much more comfortable. It’s not cheap but has been worth it for us. We’re going on about 6 months right now.


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[wesfromky]

Had my dog in to the vet today for possible arthritis, and he mentioned a new monoclonal antibody called Librela that was just approved for dogs. Monthly shot, and no idea on pricing, but maybe something to look into.

 

[bobr1]

My old lab has some osteoarthritis . Has been on glucosamine/chrondrotin seemed to help some. Tried carprofen min results . Talked to my vet i guess galliprant is a new one out . Were gonna try it a couple weeks . Anyone have any first hand experience ?

No experience with those drugs, but our dog randomly collapsed, couldn’t stand up on his own. We had to take him to the emergency vet clinic as it was night time. They gave him a meloxicam injection and we kept him on meloxicam for a month or so. Options were to put him down, try nsaid treatment, or drive 3 hours to a veterinary that had an MRI, which would be around $2000, then if he was a candidate for surgery would be another $ 5-8k for that and a long recovery. Love my dog, but he is a 11 now and decided to do the nsaids, he’s recovered about 95% from the incident, which our main vet assumes was from an issue in the cervical spine, possibly from a slipped disked or stenosis. Meloxicam helped substantially, and the vet said he would prefer to keep him on it and if he starts to get worse then we will go to steroids.

Not sure if that helps

 

[dr.mooseknuckles]

Vet here:
Really surprised you didn't see much improvement with Carprofen. Could be the dose wasn't appropriate. If your dog had anaplasmosis, that could potentially be a aggravating factor as well. Tick borne pathogens do some funky stuff.

I generally use Galliprant for dogs that have GI sensitivities with Carprofen or other similar NSAIDs. I'll also use Galliprant in dogs with mild liver/renal issues as it's generally safer on those organs for long term use. I haven't been overly impressed with it's effectiveness with the majority of patients that have been put on it, but it's better than nothing.

The Librela injection is going to be huge once it's on the market. Our clinic is supposedly going to get it sooner than most clinics for clinical trials, but don't know when that will be. We have the product for cats which blocks the same cell signaling protein (Nerve Growth Factor) from binding to it's receptor. By doing so it prevents further inflammation being stimulated within the joint. It does a great job in cats and I've had success with treating other issues off-label (urinary bladder inflammation from stress).

May want to get some rads and lab work done to make sure there isn't anything else going on.