I started with 210's then was advised by a far more experienced reloader that the 210's were not designed to reliably ignite 85+ grains of powder and I should really be using 215's. I didn't notice a huge difference in the change but when someone with more than 20 years reloading tells you something, you listen.
Not worth the risk of a hang-fire or a squib if the powder does not ignite fully. 215's were developed for that very reason and 210's are not recommended for cases with such huge volume by the manufacturer...thats really all you need to know. Ive only had to pound out one bullet stuck part way into a barrel to never want to do it again...thankfully I recognized it and didnt fire another round behind it.