If this is too much of a tangent, feel free to ignore.
I'm personally trying to find the amount of intensity that isn't damaging joints. For example I don't think hauling 100# packs around is good for the knees. I'll do it on a hunt, but I'm worried doing it weekly will be detrimental.
I've slowly worked up to 70# rucks and can do it daily, but I don't do it daily for fear of joint damage. I'm also on collagen and working on growing joint strength, meaning I started at lower weights and am working up slower than my muscles say I can. I'm not as in tune with 'good' joint soreness.
Long story short, I'm trying to listen to my body, but I haven't found a Dr. or PT with a good answer yet.
Yeah hauling around 100# on your back as exercise probably isn't the best idea
I've had good luck with "rucking" loads about 8 weeks out from hunting season (prior to that I do get a lot of day hiking/backpacking where I'm wearing a backpack, but rarely exceeds 30 #).
I'll load up weight 2-3 times/week in that 8 week lead up (I'm hiking pretty much daily)- start with 30# of sand week one & two, 45# week three & four, 60# week five & six) and then the last couple of weeks back to 30#.
Knock on wood have never had any injury with this routine and never had any drama hauling out heavier loads of meat during the season.
Some folks ruck with weight year round, if that works for them- great. I haven't found the need (I do hike almost daily and strength train twice a week year round). I have also never found the need to ruck heavier loads than 60# (probably closer to 70# with the weight of the pack, water, etc); you start getting past a certain point (imho) you needlessly open yourself up to injury