I have had the Crispi Guides for about a month, and have done a lot of short walks, but not any serious field testing. When I first got them, I detected a slight bit of heel life on my left foot. I did a few things to remedy this - dialed in the right sock to take up space, which for me is a darn tough midweight hiker or hunter, got a pair of superfeet green insoles, and started using a heel lock lace up pattern. I also tend to wear Injinji liner socks to keep sweaty toes from rubbing together.
Between all of those things and the natural break in of the boot, I feel like my heels should be fine, but I will start steeper hikes locally soon to verify. Worst case scenario, I'll bring some leukotape along to address any hot spots.
Bottom line - if you get the right size and dial them in, I would imagine that the Guides would work out well.