Warning: Anecdote here, not data
Tumeric capsule a day has provided more benefit for me (shoulder) than the glucosamine/chondroitin alone.
Never underestimate the benefits of the placebo effect. If your knees feel better taking a pill that is cheap, harmless but has only equivocal results in controlled studies, would you still take it?
The placebo effect is real , for some people . My ex FIL was a very smart guy , self made millionaire , and he was very susceptible to the placebo effect .
Two examples -
First , back in the 90's there was a supplement called Essential Minerals , it came in a bottle for like $30 a bottle .
The idea was you'd mix 1oz with a glass of water every day for all the vitamins and minerals your body needed . He swore by it , and bought it by the case and gave it to all his family members . The ex loved it and swore she felt %100 better . I was sceptical and passed . 60 Minutes ended up exposing it as a scam , the experts said it had less minerals and vitamins than the water . I was at his house watching 60 minutes , he had invited us over to gloat , he thought it would be a positive review . After the segment he got up , looked at me and said "I don't want to hear a Fookin thing from you " , and left the room .
Second , he was prone to migraines and the dr couldn't find a cause . The dr ended up giving him two pills to carry in his wallet , said only take them if you feel a migraine coming on . As long as he had the pills , he was fine , but if he left the house without his wallet , instant headache .
So yeah , for some people , but it never worked for me .
Also , I can't be hypnotized either .
I've been working out and my knees feel much better , thanks everyone for the advice .