I am left handed and have been shooting left bolt rifles since the mid 1990s. I have rifles built to my specs since that is about the only way I can get what I want. I use primarily Tikka or Rem 700 (original and clones) for a lot of my builds.
I can usually find a way to make it work for what I want. For example, as soon as MDT brought out the HNT26, I bought some of the first ones available and had the chassis milled out to accommodate the left bolt and safety - then my LH Rem 700 dropped straight in.
The below are photos of my 308 Win and my 300 Norma, both on modified RH HNT26 chassis.