ffparamedic
WKR
- Joined
- Dec 16, 2013
- Location
- S. Ga.
Interesting. I have not seen that study. If you can find a link I’d like to read it.
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CF,
No idea exactly which article Mike might be referring to but I will leave you with this one An Evidence-Based Update on Nonsteroidal Anti-Inflammatory Drugs it states "It can be seen from the Oxford League Table that few analgesics, if any, are better than NSAIDs for acute pain. All NSAIDs have a NNT of 1.6 to 3.0 on the league table. Alternative analgesics like codeine phosphate 60 mg and tramadol 50 mg, which are commonly used, have an NNT of 16 and 8, respectively. Even parenteral morphine 10 mg and pethidine 100 mg have an NNT of only 2.9." and " As a group, NSAIDs are excellent analgesics and are even more efficacious than intramuscular morphine for acute pain. However, it should be noted that the evidence for the efficacy of NSAIDs comes mainly from the study of acute pain conditions."
There is also this one An Overview of Pain Management: The Clinical Efficacy and Value of Treatment which states "In the majority of cases, an NSAID is likely to be the first line of therapy, in part because it has superior efficacy compared with acetaminophen, but does not incur the same degree of risk as some of the more potent drugs. There are risks inherent with NSAID use, but this is also true of acetaminophen—for a typically smaller therapeutic effect—and of opioids, which are associated with a spectrum of concerns of which side effects represent only 1 significant contributor."