Absolutely. I've rattled in dozens of mature bucks during all stages of the rut (have published several articles on it and give seminars on calling muley bucks). Sometimes it takes awhile for them to arrive, so you have to be patient and keep at it. It can sometimes take a half hour for a buck to come in. Sometimes they come running, but more likely they will casually wander in, looking for the source.
I start with a good clash sequence and rattle/grind for a solid minute, kicking the ground and grunting like two bucks going at it. Hold the antlers loosely so they resonate. Then I shut up and watch. After a couple minutes I do it again, but start with tip tickling before the clash-rattle-grind-grunting. Since I primarily bowhunt during November, I only tickle after I see one, to coax him into range. I presume you're rifle hunting so that won't be an issue. I keep this up off and on until I'm convinced no bucks are in the area or I decide to move.
After most of the does are bred and the bucks are roaming, looking for the few late comers, rattling can be especially productive. I've called them in from long distance during this time on quiet mornings. Set yourself up in a spot where one has to show himself in order to see where the rattling is originating.
Be patient and believe. I've been rattling them in for 35 years, despite claims by some "experts" that mature muleys can't be called in.