I'll pile on but am no expert...killed two bucks in the last two years spot & stalk. We got good at making a fairly quick 'go/no-go' decision on any animal. A great buck in a very low-probability spot got a pass, and we moved on. Next! This season I drew back four times before releasing an arrow, missed that shot, drilled the next. You have to generate a lot of chances. My hunting buddy killed the fourth buck he shot at this season. Lots of long-range shots for sure, though we both killed at about 50. Don't waste half the day going after one low-probability animal - focus on the ones that are possible.
And for love's sake, look for single animals or very small groups. Large herds are beyond hard...ask me how I know.