Not sure if anyone is following this still, but I figured I’d throw my 2 cents in, take it for what it’s worth. I shot a whitetail this season with a 100gr Annihilator, total arrow weight 406. Lighter than I want but just getting into it. It was a close shot and I was pretty high in the tree, which created a steep angle. Pushed it a little more left than I had wanted, but the arrow punched right through the top of the scapula, caught one lung, top of the heart/arteries, and passed through the shoulder meat opposite side. Deer went down within 40 yds.
Tuning them to fly with my field tips to 40 was easy for a rookie like me, and that’s as far as you could dream to shoot in the woods where this deer was. They are dull, but a stone got them decently sharp for me. The wound channel seemed great, it went through bone no problem, and the idea of cavitation created by the hole seemed accurate, given that it didn’t seal back up. The blood trail wasn’t great, but thankfully I didn’t have to rely on it. Will be using them again this year and hope to have some more input on them. Hope this helps anyone going back through old threads, always good info in the search bar.