Diamox (acetozolamide) is thought to moderate the effects of altitude by lowering the pH of the fluid surrounding the brain and spinal cord, which in turn stimulates the respiratory centers in the brain to increase resting rate and depth of breathing so that you take in more oxygen. But it’s also a diuretic, so besides losing water with every breath in dry mountain air, you will be pissing away water your body would be hanging onto under normal circumstances. You will need to consciously increase water intake if you want to stay well hydrated.
The jury is still out on ginkgo’s value to reduce the effects of altitude - but one thing that it does for sure is inhibit blood clotting by screwing with platelet function: maybe not what you want while playing rough in the backcountry. FWIW, I didn’t stay at a Holiday Inn Express last night, but I am a doctor.
I’ve taken diamox when going from sea level to 10,000+ on ski trips in years past, but have relied on a day or two of acclimation at mid altitude for most high mountain hunts. Generally felt better with the latter approach.