.300 Win Mag

[hhargrave]

I have shot a handful of mule deer with Hornady American Whitail 150 grain Interlocks

My rifle shoots these well. It’s been my go-to for muleys and antelope.

 

[Fogalo]

Another vote for 180 grain ttsx - especially if you like eating them

 

[stillwaitin]

Here are some of the animals taken with the TTSX for me:
Cow 1(wife's) 375
Pronghorn (overkill, maybe) 300
Cow 2 100
Mule deer 1 350
Cow 3 225
Mule Deer 2 290