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My factory 152 LRX loads for mine are averaging 2974...but I have 26" barrel on my XBOLT Pro Carbon with the Recoil Hawg brake on it. I like speed but take accuracy first as long as fast enough out to my usual max ranges hunting to perform well....that would be about 400 yds now for me.I had LRI build my Defiance Anti with a Shilen 1-9 chambered in 280 AI SAAMI. I've shot about 150 rounds of the 145gr LRXs with H4350 and Nosler brass. I've killed a couple bulls, had great groups with single digit SDs. I like to tinker but I can't find a good reason to with this combination. Velocity isn't anything to write home about, just under 3000FPS , but I like the temp stability of H4350.