Snakes shouldn’t be an issue but I’ve seen rattlers out in December down to the 30s. Don’t really worry about them to be honest.
Practice shooting at distance. Glass methodically; tripod is most helpful. Glass the same areas over and over an over. Very common for Coues to just appear out of
Can catch them in the open at first light but they’ll quickly head to shade. Then start picking apart every bush, shrub, tree, etc. Glass all day as you can often catch them while they get up to pee/poop, stretch their legs, and move to shade.
Dress in layers. Depending on your unit, the temperature range can be huge between night and day.
Bring a stool. Sitting pads suck here as there are many things that can easily poke through them.
If you are hunting one of the southern units, maintain situational awareness at all times. Despite what the news says, there is northbound traffic.