It depends a lot on application. SSTs come at a great price and shoot superbly well out of my Remingtons, so I use the 165gr. SSTs in my 16" .308s because I need a "softer" bullet that is going to expand reliably at the comparatively low velocities I'm shooting at.
They do tend to come apart at...
Same boat here... I couldn't push the 168s fast enough out of my .308s with Varget, especially considering my three .308s are 16" barreled. The 168s grouped a lot better than the 150s did out of both of my Remington rifles (both 1:10 - M700 & M7) but the 150s grouped better out of my Ruger (1:10...