Are you going to reload for it or buy factory ammo. The design is inherently a tad more towards improved accuracy with the PRC, shoulder angle, aligning to the bore etc. I love my PRC, but I run a 6.5 SAUM, which if run over a 6.5 PRC, and a Warbird. The PRC I grabbed because a buddy sent me a barrel for one.
I would go 300 PRC over 28 Nosler. Barrel life is going to be a bit better in the PRC as others have stated. Or stick with a 300WM because lots of factory ammo options. Going long range , run 230 A Tips